“Regulation of blood flow and cognition are extremely complex, with multiple overlapping regulatory mechanisms, paradigms and contributing structural components, and therefore more likely to be influenced by chronic supplementation.” Taking the pressure offĭietary interventions using polyphenol-rich foods, particularly those including tea, Ginkgo Biloba, cocoa and blueberry, have shown benefits on memory and learning in humans. “In terms of higher total Hb concentrations, the modulation seen in the present study may be due to the vasorelaxatory and antihypertensive properties of some of the phenolic acids (vanillic and protocatechuic acid) contained in the MC concentrate,” the study hypothesised. In addition, MC consumption significantly lowered systolic blood pressure over a period of three hours, with peak reductions of six millimetres of mercury (mmHg) one hour after drinking the cherry juice when compared to the placebo. There were differences of significance in the total Hb and oxygenated Hb concentrations one hour after drinking the cherry juice. In the study, 27 subjects aged 45–60 years received either a 60 millilitre (ml) dose of MC juice or a placebo.Ĭerebrovascular responses, cognitive performance and blood pressure were assessed at the start of the study and at one, two, three and five hours following consumption. It is thought these polyphenols have some role to play in controlling blood flow parameters that include increasing nitric oxide production and antioxidant status, reducing lipid oxidation and inhibiting inflammatory pathways. This type of sour cherry has been the subject of a number of studies that have isolated the fruit’s rich polyphenol content that includes flavonoids such as isorhamnetin, quercetin, catechin, and anthocyanins. Here, men with early symptoms of hypertension reduced this by 7% after drinking Montmorency cherry juice. The same team have previously found drinking this juice to be effective in reducing high blood pressure. One explanation could be in its efficacy in halting the decline in cerebral blood volume and metabolism of oxygen often seen in the ageing process. The findings, made by a team from Northumbria University in the UK, found evidence of increased cerebral blood flow (CBF) to the brain’s cerebral cortex, indicated by increased haemoglobin (Hb) concentrations.ĭespite this observation, the findings did not translate to improvements in cognition or mood post-consumption.Ī number of dietary interventions using polyphenol-rich foods, particularly those including tea, ginkgo biloba, cocoa and blueberry, have shown benefits on memory and learning in humans. The gut-brain axis: Psychobiotic opportunity in 25 countries.Uncovering white spaces – Probiotics for a smooth menopause transition.Uncovering White Spaces – Probiotics for Pets.POSTbiotics – New Tools in Microbiome Modulation.After the pandemic: Business lessons and insights from 25 probiotic supplement e-markets.These data will provide information on the ability of TMCJ to affect blood flow and vascular function. This study will also examine digital volume pulse and pulse wave analysis. This study will examine the influence of tart Montmorency cherry juice on cardiovascular function, specifically arterial stiffness by pulse wave velocity and blood flow in the microcirculation by laser Doppler imaging. However, the bioavailability of all the compounds in Tart Montmorency Cherry Juice and their efficacy with respect to vascular function has not been fully determined. Impaired function of the lining of blood vessels (endothelial dysfunction) has been linked to increased risk of cardiovascular disease. Several of these compounds, are known to be vasoactive and improve blood vessel function by increasing bioavailability of vasodilators (Mudnic et al 2012), reducing vasoconstrictors (Broncel et al 2010), decreasing platelet aggregation (Hubbart et al 2006) and increasing blood vessel dilation (Schroeter et al 2006). Tart Montmorency cherries have been shown to be high in numerous phytochemicals (Wang et al 1999 Seeram et al 2001). Research provides evidence that consumption of a diet high in plant foods and rich is polyphenols is associated with a reduction in the incidence of cardiovascular disease (Hung et al 2004). Given the global health issues associated with poor cardiovascular function, interventions that help reduce the severity, with emphasis on prevention would not only have economic implications, but would also improve health, wellbeing and quality of life.
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